Botulinum Therapy for Dystonias


Botulinum therapy is one of the most effective and safe methods for treating various forms of dystonia. The method is based on the targeted injection of botulinum toxin into overactive muscles in order to relax them, reduce pathological activity and improve the patient’s quality of life.
Dr. Lidiia Prakhova has experience in diagnosing and treating dystonias, including severe and rare forms, and performs high-precision injection treatment using anatomical landmarks, ultrasound and EMG.

Which dystonias are treated with botulinum therapy

Cervical dystonia (spasmodic torticollis)

The most common form of focal dystonia, manifested by:
  • pathological head turn (torticollis);
  • tilt (laterocollis);
  • extension (retrocollis) or flexion (anterocollis);
  • neck pain, muscle tension, headaches.
  • Botulinum therapy is a first-line method and allows significant reduction of spasm, pain syndrome and improvement of head position.

Blepharospasm

Bilateral involuntary spasms of the orbicular eye muscle:
  • frequent blinking;
  • “crinkling” of the eyes;
  • difficulty opening the eyelids;
  • photophobia, tearing.
  • The toxin in small doses is injected into the orbicular eye muscle and ensures long-lasting (3–4 months) symptom control.

Hemifacial spasm

Involuntary contractions of muscles on one half of the face:
  • eyelid twitching;
  • spasms of the cheek, mouth;
  • facial asymmetry;
  • social and functional discomfort.
  • Injections are carried out into key mimic muscles, which reduces spasm without affecting facial symmetry and natural mimicry

Dystonias of the limbs

Include:
  • writer’s cramp;
  • musician’s dystonias;
  • focal spasms of the forearm and hand;
  • foot dystonias.
  • The method enables restoration of precision of movement, reduction of painful spasm and improved functionality.

Advantages of botulinum therapy

  • High efficacy — significant reduction of spasms in most patients.
  • Minimal side-effects with proper technique.
  • Local action — no systemic impact on the body.
  • Proven safety with years of use.
  • Ability to tailor dosing to individual patient characteristics.
  • Short procedure time and quick return to normal activity.

How the procedure is performed

  • Consultation and clarification of dystonia type;
  • Neurological examination;
  • MRI/EMG analysis if necessary;
  • Selection of optimal muscle group.
  • Choice of agent and dosage. Original preparations are used: Botox®, Dysport®, Xeomin® depending on the clinical task.
  • Injections into the selected muscles; procedure takes 10–20 minutes; a fine needle is used; injections are performed under ultrasound guidance to achieve very high precision. In some cases EMG-guided targeting is used for maximum accuracy.
  • Effect: First results appear within 3–7 days; full effect by day 10–14. Duration of action — 3–4 months.

When botulinum therapy is recommended

  • Pronounced or painful spasms;
  • Disturbance of head or eye position;
  • Impairment of writing, work or daily activity;
  • Intolerance or insufficient effect of oral medications;
  • Cosmetically significant facial asymmetry in dystonias.

Possible side-effects

Rare and usually reversible:
  • Weakness of adjacent muscles;
  • Mild tenderness at the injection site;
  • Bruising;
  • Transient mimic asymmetry.
  • With proper technique the risk is minima

Consultations & appointments

Consultations (and botulinum therapy) are carried out at the outpatient clinic of the Shamir Medical Center (Assaf Harofeh). Adult patients (18+).
For an appointment: 08-977-97-75, 08-977-91-45
neuro@shamir.gov.il, 089779758@shamir.gov.il
Dr. Lidiia Prakhova
Author
Dr. Lidiia Prakhova
Neurologist, expert in demyelinating diseases, migraine and botulinum toxin therapy

Dr. Prakhova is a neurologist practicing in Israel. She consults patients with MS, NMOSD, MOGAD, chronic migraine, dystonia and spasticity.

  • Over 35 years of clinical experience in neurology.
  • Main specialization — demyelinating CNS diseases and migraine.
  • Experience with modern MS/NMOSD/MOGAD therapies.
  • Advanced botulinum toxin therapy training.
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